Malignant lymphoma of the oral cavity is rare (2-3%). The gingival vestibule and Waldeyer’s ring seem to be the most frequent sites of occurrence whereas the lingual and buccal mucosa is rarely involved. We here present a case of Bcell lymphoma in a 55 year old male who presented with a mass lesion primarily involving the tongue. Although lymphoma of tongue is very uncommon, it should always be...

Human immunodeficiency virus (HIV) infection is endemic in South Africa. Non-Hodgkin lymphoma (NHL) occurs with increased frequency in HIV seropositive individuals. The increase in NHL has been more marked in the last decade, with HIV being the major contributor to this increase. More than 70% of the adult NHL patients at Chris Hani Baragwanath Academic Hospital (CHBAH), Soweto, Johannesburg, a...

Diffuse Large B-Cell Lymphoma (DLBCL) is the most common type of Non-Hodgkin Lymphoma (NHL) which includes about (25%) of the cases. Patients with DLBCL have a rapidly growing mass that is located in the neck or abdominal region. Multiple Myeloma Oncogene (MUM1) has an important role in lymphoid cell differentiation. MUM1/IRF4 is as oncogene related to myeloma and translocation (p25; q32), t (6...

4. Dabski K, Banks P, Winkelmann RK. Clinicopathologic spectrum of cutaneous manifestations in systemic follicular lymphoma. A study of 11 patients. Cancer. 1989;64:1480--5. 5. Senff NJ, Hoefnagel JJ, Jansen PM, Vermeer MH, van Baarlen J, Blokx WA, et al. Reclassification of 300 primary cutaneous Bcell lymphomas according to the new WHO-EORTC classification for cutaneous lymphomas: comparison w...

Primary spinal cord lymphomas are rare, and either extra-/intradural masses with leptomeningeal infiltration or intramedullary in nature. These two patterns of growth do not generally overlap. The authors present a patient with a diffuse large Bcell lymphoma involving the sacral nerve root, extension to extradural space, and the cranial nerve. The literature regarding isolated nerve root lympho...

LyP: lymphomatoid papulosis INTRODUCTION Lymphomatoid papulosis (LyP) is an indolent skin disease characterized by chronic, recurrent, selfhealing papules and nodules with histologic findings suggestive of malignant lymphoma. LyP is classified as a CD301 cutaneous lymphoproliferative disorder according to the 2005 World Health Organization/ European Organisation for Research and Treatment of Ca...